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Steigenberger Hotel Berlin will host Targeting Microbiota World Congress 2017 and will offer you privileged rates for your early booking!

Steigenberger Hotel Berlin

Los-Angeles-Platz 1 | 10789 Berlin, Germany

Website available here

The Steigenberger Hotel Berlin is located in the center of the City West – only a 5-minute walk from Kurfürstendamm. The Brandenburg Gate, the Reichstag and Checkpoint Charlie can be reached within 20 to 25 minutes using public transport.

You'll be amazed by the outstanding design when you enter any of the 398 rooms and suites. Equipped with air-conditioning, minibar, Nespresso coffee machine, flat-screen TV with Sky and safe: you're sure to enjoy a relaxing stay in Berlin.

Book your room at Steigenberger Hotel Berlin with special rate before September 25!

You can select between two categories:

• Superior Room

Feel at home straightaway in our 22 to 24sq.m. Superior Rooms with a view to the hustle and bustle between Kurfürstendamm and Los Angeles Square or to the quiet inner courtyard.
Fully equipped bathroom with bathtub or shower, individually controlled air conditioning, complimentary Wireless High Speed Internet (HSIA), complimentary bottle of mineral water during the stay, complimentary tea and coffee making facilities, flat screen.

EUR 139.00 per room and night, single occupancy, included breakfast

EUR 159.00 per room and night, double occupancy, included breakfast

• Deluxe Room

The Deluxe Rooms with a size of 24 to 26sq.m. on the 5th and 6th floor are rooms for relaxation with a modern design and a view to the quietly situated park of the Los Angeles Square.
Fully equipped bathroom with bathtub, bathrobe & slippers, individually controlled air conditioning, complimentary Wireless High Speed Internet (HSIA), daily complimentary bottle of mineral water, complimentary tea and coffee making facilities, Nespresso machine, welcome treatment from the General Manager, discount voucher for shopping at the Galleries Lafayette, daily newspaper, turn down and shoe shine service, large flat screens. 

EUR 169.00 per room and night, single occupancy, included breakfast

EUR 189.00 per room and night, double occupancy, included breakfast

The 2016 is approaching to the end and a fantastic year will come...

Dear estimated Collegues,

The 2016 is approaching to the end and a new fantastic year will come. The 2016 sees in pubmed the amazing amount of more than 4.000 articles regarding the Microbiota….the meaning is that we are on the right way!! Indeed, more and more outstanding experts are continuously involved in the microbioma study and the interest increases day by day, especially in the biomedical field.

Looking at this, we are thinking at the new preliminary program for the next 2017 in order to involve the best scientists around the world, and especially those who are also able to create networks and share informations.

Here further topics we should also focus our attention for the next agenda on 2017:
- Nasal-oral-bronchial microbioma: any markers for healthy?
- Breast microbioma: which future for our children?
- Vaginal microbioma: still lactobacilli?
- Gut microbioma: transplantation, diseases and future evolutions
- Skin microbioma: intestinal or topical solution?
- Organs-gut axes: only brain?
- Technical and bioinformatics tools for studying microbioma
- Guidelines and Miscellanea: right samples for the right microbioma

We hope of course to receive more suggestions and especially productive applications for participating to the 5th International Congress of Microbiota.

Wishing you and you families a prosperous and fruitful new years, best regards and see you soon in Paris.

Prof. Lorenzo Drago
President of ISM

Special Session on Fecal Microbiota Transplantation: All you need to know from A to Z about FMT

This special session will be animated by Pr Peter Konturek, from the Teaching Hospital of the University of Jena, Germany.

Who is Pr. Peter Konturek?

Read more...

Pr Harald Weiner from Harvard University will introduce Targeting Microbiota 2016

The Scientific Committee is honoured to welcome Pr Harald Weiner, from Harvard University, USA to introduce the 4th World Congress on  Targeting Microbiota to be held at Institut Pasteur, Paris on October 17-19, 2016.

Read more...

Strategic questions by Marvin Edeas, from Institut Cochin, INSERM U1016

During Targeting Microbiota 2016 World Congress which will be held from October 17 to 19, at Pasteur Institute, Paris, more than 100 communications (oral & poster) will be presented during three days.

With more than 400 attendees coming form academies and industries, we asked Marvin Edeas, from Institut Cochin, INSERM U1016, University Paris Descartes and as chairman of the scientific committee of Targeting Microbiota 2016 to comment about the strategic points and questions which will be discussed during Targeting Microbiota 2016.

In order to have a better picture of microbiota 2016 advances, we need to answer many questions:
- Can we modulate the quality and diversity of our microbiota?
- Where is the red line of the gut microbiota manipulation?
- What are the strategic mediators of gut microbiota?
- What is the perfect microbiota "signature" and how to use it as a biomarker to "predict" and/or treat many diseases?
- It is very easy today to analyze and study the microbiota, however it is very difficult to interpret the results. How the skills of bioinformaticians will lead us to a "golden standard"? 
- Can policy makers clarify the health claims and fecal microbiota transplantation regulation?

Marvin Edeas concluded: I wish that we have a strong discussion between all the actors to progress in our strategies to predict and treat many microbiota related diseases.

For more information about Targeting Microbiota 2016: www.microbiota-site.com

Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics

According Pr Roberto Pacifici, from Emory University School of Medicine, USA: "A eubiotic microbiota influences many physiological processes in the metazoan host, including development and intestinal homeostasis. Here (in our study), we have shown that the intestinal microbiota modulates inflammatory responses caused by sex steroid deficiency, leading to trabecular bone loss. [...] In germ-free (GF) mice, sex steroid deficiency failed to increase osteoclastogenic cytokine production, stimulate bone resorption, and cause trabecular bone loss, demonstrating that the gut microbiota is central in sex steroid deficiency–induced trabecular bone loss. [...] Together, these data highlight the role that the gut luminal microbiota and increased gut permeability play in triggering inflammatory pathways that are critical for inducing bone loss in sex steroid–deficient mice. Our data further suggest that probiotics that decrease gut permeability have potential as a therapeutic strategy for postmenopausal osteoporosis."

The scientific committee of the International Society of Microbiota is honoured to welcome Pr Pacifici during the 4th World Congress on Targeting Microbiota to be held on October 17-19, 2016 at Institut Pasteur, Paris.

For more information and registration: www.microbiota-site.com

Marvin Edeas, Chairman of ISM

Lung microbes and their effect on asthma: A new strategic topic which will be discussed during Targeting Microbiota 2016

During the 4th Congress on Targeting Microbiota, Dr. Muriel Thomas from INRA Jouy, France will be presenting the topic of "Lung microbes and their effect on asthma".

The following main questions will be anserwed during the congress :

1. What is the Influence of germ free status on lung physiology in mice?
2. Can we isolate viable and functional bacteria in the lung at steady state or during asthma ?
3. Do the Lung bacterial strains display specific immunoregulatory properties ?
4. Do the lung strains modulate a pathology like asthma in mice neonates ?

The research highlights:

1. • The absence of microbes  affects lung physiology and immunity
2. • Lung primocolonization is a highly susceptible period for asthma
3. • Lung bacterial strains display ex vivo and in vivo immunoregulatory properties
4. • The equilibrium between protective and exacerbating strains modulate asthma feature

If you are interested to know more about Dr Thomas' researches, do not hesitate to join the participants by registering here: www.microbiota-site.com

Marvin Edeas  Chairmen of ISM

More than 350 attendees participated during Targeting Microbiota Three-day congress

Targeting Microbiota 2016 was the perfect opportunity to meet all the leaders in the field of microbiota. If you are interested to contact specific persons, please let us informed and we will organize your exchanges.

Read more...

Tools and approaches to achieve strain resolution analyses of the microbiota

Dr. Knut Rudi, from the Norwegian University of Life Sciences will present his research about the "Tools and approaches to achieve strain resolution analyses of the microbiota". He will specially highlight the role of the gut microbiota mobilome and the potential of pathogen transmission of antibiotic resistance during the 4th World Congress on Targeting Microbiota to be held on October 17-19 at Institut Pasteur.

During his presentation, Dr Rudi will answer the following questions:

1. How can we determine the number of bacterial strains colonizing   the human gut?
2. What are the main vectors for horizontal gene transfer of antibiotic resistance in the gut?
3. What are the taxonomic associations for horizontal gene transfer in the gut?

If you would like to know more about Dr. Knut Rudi' study, don't hesitate and come.

For more information: www.microbiota-site.com

Moody microbes or fecal phrenology: what do we know about the microbiota-gut-brain axis

During the 4th World Congress on Microbiota, Dr. Paul Forsythe from the McMaster University of Canada will be speaking about his researches about the moody microbes or fecal phrenology.

According to Dr Forsythe, the microbiota-gut-brain axis is a term that covers a broad set of functions and interactions between the gut microbiota, the endocrine, immune and nervous systems, and the brain.

At first sight it appears gut microbes are largely responsible for the development, maturation and adult function of the enteric nervous system as well as the blood brain barrier, microglia and many aspects of the central nervous system structure and function. Communication between gut and brain depends on both humoral and nervous connections. Since such communication is bi-directional and occur through complex pathways, it is perhaps not surprising that while striking observations have been reported, they have often either not yet been reproduced or their replication by others has not been successful. Given the state of the art in this exploding field and the hopes, as well as the skepticism, which have been engendered by its popular appeal, this presentation will explore recent examples of evidence in rodents and data derived from studies in humans, which offer insights as to pathways involved. 

For more information about Targeting Microbiota World Congress and Dr Forsythe's presentation: www.microbiota-site.com

Marvin Edeas, Chairman of ISM

Systemic immunity against selected gut microbes protects from atherosclerosis and wetsern-diet-related inflammation

Common features of immune-metabolic and inflammatory diseases such as metabolic syndrome, diabetes, obesity and cardiovascular diseases are an altered gut microbiota composition and a systemic pro-inflammatory state. In this publication, Pr Canducci and his team demonstrate that active immunization against the outer membrane protein of bacteria present in the gut enhances local and systemic immune control via apoE-mediated immune-modulation. Reduction of western-diet-associated inflammation was obtained for more than eighteen weeks after immunization. Immunized mice had reduced serum cytokine levels, reduced insulin and fasting glucose concentrations; and gene expression in both liver and visceral adipose tissue confirmed a reduced inflammatory steady-state after immunization. Moreover, both gut and atherosclerotic plaques of immunized mice showed reduced inflammatory cells and an increased M2 macrophage fraction.

These results will be presented during Targeting Microbiota World Congress, by Pr Filippo Canducci from San Raffaele Scientific Institute IRCCS, Italy, to be held at Institut Pasteur on October 17-19, 2016.

For more information: www.microbiota-site.com

The first Symposium dedicated to Skin Microbiota gathered around one hundred specialists on skin in Paris

The first symposium on Skin Microbiota held on June 17 was a huge success. Around one hundred participants involved in skin microbiota gathered in Paris and discussed the recent scientific advances and innovations in the field of Skin Microbiota.

Two scientists were awarded for their scientific contribution:
Dr Tewes Tralau presented a talk about "Insights on Human Microbiota & Focus on Skin Microbiota"

Dr Chris Callawaert presented a talk about "The Textile and Armpit Microbiome in Relation to Body Odor and the Influence of Deodorants and Antiperspirants"

To access to the program of Skin Microbiota 2015, please click here.

To access to the pictures, please click here.

To order the abstracts book, please contact us.

Microbiota and Colorectal Cancer: ISM is honoured to welcome Pr Iradj Sobhani as distinguished speaker

As Editor-in-Chief of the Journal of the International Society of Microbiota, Pr Iradj Sobhani was invited by the scientific committee to give a strategic presentation about "Anti cancer chemotherapy and Microbiota changes in Colorectal cancer" during the 4th World Congress on Targeting Microbiota to be held at Institut Pasteur on October 17-19, 2016.

According Pr Sobhani: "A colon cancer related dysbiosis has been reported and specific bacteria from either stool Microbiota or gut Microbiota have been characterized. Whether human microbiome might impact response of tumour to therapies is now a crucial issue. Several preliminary studies conducted in animals as well as in human support this hypothesis. W’ll summarize these data and give an overview on our preliminary pilot study under Folfox therapy."

For more information about the congress: www.microbiota-site.com

Marvin Edeas - Chairman of the scientific committee

Olfaction & Microbiota: What is the impact of microbiota on odorant detection and olfactory preferences in mice?

Dr Nicolas Meunier from Neurobiologie de l'Olfaction et Blosenseur (NBO) at INRA, France is invited to give a presentation about the impact of microbiota on odorant detection and olfactory preferences in mice.

During his presentation, Dr Meunier will answer the following questions:

• Does the absence of microbiota alter the olfactory epithelium development?
• Is the detection of odorant different in germfree mice?
• Does the microbiota alter the interest of mice to odours?

If you are interested to know more about the olfaction and microbiota, don't hesitate to register for Targeting Microbiota World Congress.

Targeting Microbiota 2016
www.microbiota-site.com

What is the gut microbiota-bone axis? Recent advances and perspectives

One of the strategic question of Targeting Microbiota 2016 will be "What is the gut microbiota-bone axis?"

This strategic question will be answered by Dr Elena Comelli, Lawson Family Chair in Microbiome Nutrition Research, Faculty of Medicine, University of Toronto, Canada.

She will also highlight the mechanisms underlined by the gut microbiota-bone axis and will answer the question "Can we use diet to beneficially impact this axis?"

If you are interested to know more about this strategic topic, come and register on www.microbiota-site.com

The butyrate revival. Short chain fatty acids as key mediators of gut microbiota

Pr Hervé Blottière, the Director of Research at INRA, the French National Research Institute for Agricultural and Food Research, will join the 4th Congress on Targeting Microbiota and present his research topic of "The butyrate revival. Short chain fatty acids as key mediators of gut microbiota".

The following questions will be discussed during the congress:

1. Is depletion of butyrate metabolic pathway genes in gut microbiome a common trait of  disease-associated dysbiosis?
2. Can we consider short chain fatty acids as essential cell-signaling modulators in host cells through Lysine/Histone Deacetylase inhibition and G-protein coupled receptor activation ?
3. What is the effect of SCFA on the intestinal immune cells ?

If you are interested to know more about Pr Blottière's researches, do not hesitate to join the participants by registering here: www.microbiota-site.com

Transition from an infant- to adult-like gut microbiota – where do the bacteria come from?

During the 4th World Congress on Targeting Microbiota, Dr Ekaterina Avershina, from the Norway University of Life Sciences will talk about the "Transition from an infant- to adult-like gut microbiota – where do the bacteria come from?".

During her presentation, she will highlight and answer for following questions:

1. How can we determine the number of bacterial strains colonizing   the human gut?
2. What are the main vectors for horizontal gene transfer of antibiotic resistance in the gut?
3. What are the taxonomic associations for horizontal gene transfer in the gut?

If you are interested to know more about this strategic topic, you can register for the 4th World Congress on Targeting Microbiota by clicking here.

The International Society of Microbiota
www.microbiota-site.com

The challenge of the bioinformatics, integrating clinical and microbiome data will be discussed during Targeting Microbiota Congress 2016

During Targeting Microbiota World Congress 2016, Dr Velma Aho from the University of Helsinki will take about the challenge of the bioinformatics, integrating clinical and microbiome data. She will especially present the examples from gut, oral and nasal microbiota in Parkinson's disease.

At the end of Dr Aho's presentation, the following questions will be answered:

- What to consider when designing a microbiome study?

- How to integrate clinical and microbiome data?

- What can we say about the associations between Parkinson’s disease and gut, oral and nasal microbiota?

If you are interested to know more about bioinformatics and microbiota data management, you can join the participants of Targeting Microbiota World Congress by registering here.

www.microbiota-site.com

 Marvin Edeas, Chairman of ISM

Maternal microbiota sets neonatal innate immune system development

Dr Mercedes Gomez de Agüero from the University of Bern in Switzerland was invited by the scientific committee of the International Society of Microbiota to present her researches about the maternal microbiota and the neonatal innate immune system development.

The following questions will be answered by Dr Gomez during the congress:

1. When the impact of the microbiota in the development of the immune system starts?
2. What is the role played by the maternal antibodies in the impact of maternal microbiota in the development of neonatal immune system?
3. Which kind of bacterial products would be involved in the effect of maternal microbiota in the shaping of the neonatal immune system?

According to Dr Gomez, Mammalian, born from a sterile environment in the maternal uterus, get colonized by a millions of microorganism at birth. How the immature neonatal immune system of the newborn is prepared to this colonisation was not clearly understood. Using an auxotrophic genetically modified strain of Esc Maternal microbiota sets neonatal innate immune system development herichia coli, we reversible colonised pregnant germ free mice and analysed by flow cytometry and RNA sequencing the impact of maternal microbiota on the development of immune system in the pups. [...] The offspring from gestational colonized mothers were protected against microbiota challenge preventing bacterial translocation to mesenteric lymph nodes and modulating gene expression. Our results reveal the tremendous role played by maternal microbiota and antibodies in setting the baseline of the innate immune system in the neonates. 

For more information about this strategic topic, don't hesitate to register on www.microbiota-site.com

Important human microbial ecological system modulator - FMT or one of the best clinical applications of epigenetics in gastroenterology

During Targeting Microbiota World Congress 2016, Dr. Diana Zandere from the University of Riga, Latvia will talk about the important human microbial ecological system modulator - FMT (fecal microorganism transplantation) or one of the best clinical applications of epigenetics in gastroenterology.

At the end of Dr Zandere's presentation, the following questions will be answered:

1. Have there been FMT donor selection with appropriate donor-recipient sex matching (i.e.young female to female, young male to male and so on) in order to enhance FMT colonization success?
2. Should donors or recipients adhere for a certain period of time to agluten diet for better therapeutic gain (think zonulin-occludin systems and/or N-(phosphonomethyl) glycine?
3. Is nutritional background as an important GI microbiome modulator & epigenetic modulator being investigated enough in connection to FMT and/or probiotic or sinbiotic "loading"? Polypharmacy + probiotics without true enteric coating + frozen unmatched FMT donor material + long term nutritional management absent +xenoestrogens+ recipient with organ deficiency=...?

If you are interested to know more about human microbial ecological system, you can join the participants of Targeting Microbiota World Congress by registering here.

www.microbiota-site.com

Marvin Edeas, Chairman of ISM